I doubt Arsenal would be too tired to play for tomorrows game. Nottingham isn't a good team, not this year at least and there is a big chance that Arsenal could lose to them and because of that I honestly expect a chance for Arsenal to get another win. They are leading the league and yes Liverpool tie was sad, they could have been leading with two more points if they could, but at the end of the day we are seeing them do fine.
Arteta must have expected this and rotation is likely to take place for some positions because the break is only 2 days obviously it's a little more complicated but I'm still quite confident in Arsenal's performance for this match.
They will face Nottingham who are currently in a difficult state to predict their performance because sometimes they are quite good but on the other hand they also look quite bad and are not ready for the match.
So I am still optimistic even though Arteta makes this an arena for some rotation players because still their target is 3 points to make their point gap defense with Manchester City especially City's chance with their current performance is still not very good and I expect more for Manchester United to survive well in the Manchester derby this time.